But Sinner soon quashed those dreams, breaking back as Fritz attempted to serve for the set and doing the same two games later to wrap up the win after two hours and 16 minutes.
It was more straightforward in New York as he rarely looked troubled by Fritz, who struggled to build any momentum.
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Sinner said the title "meant so much because the last period of my career was not easy" before he became tearful and dedicated the victory to his aunt.
"It's nice I can still share these moments with her. She is an important person in my life and still is.
World number one Jannik Sinner insists that fans have been "positive" in their response to his doping test controversy but he will tackle his locker room critics... 28 Aug
It marks a new era of tennis as 24-time major winner Novak Djokovic, who was knocked out in the third round, ends the year without a Grand Slam title for the first time since 2017.
Refusing to dwell on the first set, Fritz improved and made the second a closer affair, losing just two points in four service games.
However, Sinner then underlined his status as world number one, upping the ante when it 米兰体育app mattered most to strike the crucial blow as Fritz served to stay in the set at 5-4 down.
It comes just 19 days after it was revealed he had been cleared of any wrongdoing after twice testing positive for a banned substance in March.
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Concussions in amateur sport are not linked to increased long-term risks of cognitive decline, according to a study published on Wednesday. 04 Sep
He was not at the peak of his powers for the entire two weeks, but still only dropped two sets and saved his best for the final.
Cheered on by a home crowd packed with celebrities and sporting stars, Fritz got off to a shaky start when he dropped serve in the first game.